Pork Tenderloin — Sous Vide (140°F, 3–5 hrs) | Dr. Terry Simpson
Pork Tenderloin — Sous Vide
Equal-parts rub → 140°F water bath (3–5 hrs) → hot, fast sear. Blushing, tender, and foolproof.
Hands-on: ~10 min Sous vide: 3–5 hrs @ 140°F Yield: 4–6 servings

Rubbed, sous-vided, then seared for 90–120 seconds per side.
Jump to: Ingredients · Method · Why sous vide works · Notes · Nutrition · Med-Diet Points
Ingredients
- 1 whole pork tenderloin, trimmed
- Rub (equal parts): kosher salt, black pepper, sweet paprika, brown sugar
- Rub (half-parts): dry mustard, cayenne
- Neutral oil for skillet sear (optional)
Scaling tip: For one tenderloin, start with ~1 Tbsp each of salt, pepper, paprika, brown sugar + ~1/2 Tbsp each of dry mustard and cayenne. Mix, then coat all sides.
Method
- Rub & bag: Mix rub; coat tenderloin generously. Vacuum-seal or use a zip bag (water-displacement method).
- Sous vide: Cook at 140°F / 60°C for 3–5 hours.
- Dry aggressively: Remove and pat completely dry—surface moisture prevents browning.
- Sear hot & fast: Preheat a grill or skillet until very hot. Sear 1½–2 minutes per side for color.
- Serve: Rest briefly; slice into medallions and serve with the pan juices.
Why sous vide works for lean pork
- Precision without overshoot: A 140°F / 60°C bath keeps the entire tenderloin at the target—edge-to-edge pink—so there’s no grey, overcooked ring from hot pans or fluctuating ovens.
- Protein science = juicy texture: At ~130–140°F, myosin sets (tender structure) while actin—which squeezes out moisture—hasn’t fully tightened (that happens closer to the mid-150s°F). Result: tender, sliceable, still-juicy meat.
- Time gently tenderizes: Connective tissue softens with time at moderate temperature; 3–5 hours makes a lean cut forgiving without drying it out.
- Moisture retention: Bagging limits evaporation, so juices stay in the meat. Pat dry after the bath, then do a fast, hot sear for color without overcooking the interior.
- Food safety by time × temp: Extended time at a stable temperature pasteurizes the center; the quick finishing sear adds surface safety and flavor.
- Repeatable & stress-free: The wide 3–5 hour window makes dinner timing easy—perfect for guests.
Preference tweaks: 140°F / 60°C is blushing and very tender. If you like slightly firmer slices, try 145°F / 63°C. If you prefer ultra-soft, you can go 135–138°F with a longer time—just finish with a very hot, brief sear.
Notes & Food Safety
- USDA conventional guidance: Whole cuts of pork are considered safe at 145°F (63°C) + 3-minute rest when cooked conventionally (oven/pan/grill). Use a thermometer if not using sous vide.
- Flavor levers: Swap paprika for smoked paprika; add garlic powder or fennel seed if you like.
- Serving ideas: Pair with roasted vegetables, green beans with mustard, or a big Mediterranean salad.
Nutrition (estimates)
Rub contributes minimal carbs; numbers vary with trim and portion size.
*Depends mainly on salt level in the rub.
Mediterranean Diet Points
Red meat ≤ 4 oz = 1 point Plant sides + EVOO = +1–2 points
Let pork be the accent; build the plate around vegetables, beans, and whole grains.
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